Clinical Trials

A Feasibility Study Exploring the Effect of the
MobiusHD Device in Patients with Heart Failure

Study Design

  • Prospective, open-label clinical trial
  • Subjects to be seen at the following intervals: 1 week, 1, 3, 6, 12, 18, and 24 months

Key Eligibility Criteria

  • Suitable carotid artery anatomy
  • Stable Guideline Directed Medical Therapy (GDMT)
  • LVEF ≤ 40%
  • NYHA Class III
  • 6MWD distance of 150 to 400m
  • NT-proBNP ≥ 400 pg/mL

Confirmatory Evidence (n=21)

  • All patients were successfully implanted with the MobiusHD device in pre-procedurally determined locations
  • Initial evidence through 12 months FU shows favorable effects on cardiac function and clinical profile
  • Improved quality of life (KCCQ OSS)
  • Increased exercise tolerance 6MWD
  • Improved NYHA class